63049-83-2Relevant academic research and scientific papers
Investigation of the synthesis of benzofuroindolines from N-hydroxyindoles: An O-arylation/[3,3]-sigmatropic rearrangement sequence
Tomakinian, Terry,Kouklovsky, Cyrille,Vincent, Guillaume
, p. 1269 - 1275 (2015)
Abstract We report the demonstration that sensitive N-hydroxyindoles can be O-arylated under transition-metal-free conditions with biaryliodonium salts. The subsequent spontaneous [3,3]-sigmatropic rearrangement delivers benzofuroindolines derived from tryptamine. We also describe the practical synthesis of N-hydroxyindoles by oxidation of indolines with m-CPBA.
