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2-Chloro-3-[(4-ethoxyphenyl)amino]naphthalene-1,4-dione is a complex organic chemical compound with the molecular formula C18H14ClNO3. It is characterized by a naphthalene-1,4-dione core, which is a derivative of naphthalene with two carbonyl groups at the 1 and 4 positions. One of the key features of 2-chloro-3-[(4-ethoxyphenyl)amino]naphthalene-1,4-dione is the presence of a 2-chloro group, which introduces a chlorine atom at the 2 position of the naphthalene ring. Additionally, the compound has an amino group attached to a 4-ethoxyphenyl moiety at the 3 position, which adds a layer of complexity to its structure. This ethoxyphenyl group consists of a phenyl ring with an ethoxy substituent at the 4 position, further enhancing the molecule's reactivity and potential applications. The compound's unique structure may endow it with specific chemical properties and reactivity, making it a subject of interest in various fields, including pharmaceuticals and materials science.

6305-25-5

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6305-25-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6305-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,0 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6305-25:
(6*6)+(5*3)+(4*0)+(3*5)+(2*2)+(1*5)=75
75 % 10 = 5
So 6305-25-5 is a valid CAS Registry Number.

6305-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-3-(4-ethoxyanilino)naphthalene-1,4-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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More Details:6305-25-5 SDS

6305-25-5Relevant academic research and scientific papers

Thermolysis of 2-azido-3-(R-anilino)-1,4-naphthoquinones. Nitrene insertion versus hydrogen abstraction

Cárdenas-Chaparro, Agobardo,Leyva, Elisa,Loredo-Carrillo, Silvia E.,Martínez-Richa, Antonio,Platz, Matthew S.

supporting information, (2020/03/03)

2-chloro-3-(R-anilino)-1,4-naphthoquinones react with sodium azide upon refluxing in DMF. The thermochemistry of 2-azido-3-(R-anilino)-1,4-naphthoquinone is strongly modified by the substituent on aniline. Having an strong electron-donor like O-R results

Synthesis and cytotoxicity of 6,11-Dihydro-pyrido- and 6,11-Dihydro-benzo[2,3-b]phenazine-6,11-dione derivatives

Kim, Young-Shin,Park, Se-Young,Lee, Hyun-Jung,Suh, Myung-Eun,Schollmeyer, Dieter,Lee, Chong-Ock

, p. 1709 - 1714 (2007/10/03)

6,11-Dihydro-pyrido[2,3-b]phenazine-6,11-diones and 6,11-dihydro-benzo[2,3-b]phenazine-6,11-diones were synthesized from 6,7-dichloro-5,8-quinolinedione and 2,3-dichloro-1,4-naphthoquinone. The study on the cytotoxicity on these products revealed that the pyridophenazinediones, tetracyclic heteroquinone analogues with three nitrogen atoms exhibited a high cytotoxicity on several human tumor cell lines. Compound 9c and 9e showed in vitro antitumor activity comparable or superior to doxorubicin against the human ovarian tumor cells (SK-OV-3) and the human CNS cells (XF 498). The IC50 value for compound 9e was 0.06 μM against the human CNS cells (XF 498), which was 2.6 times higher than that (0.16 μM) of doxorubicin. In addition, the X-ray crystallographic analysis of two phenazinedione derivatives (9b,c) showed clearly the exact position of the nucleophilic substitution of 6,7-dichloro-5,8-quinolinedione.

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