6305-66-4

Basic information

• Product Name: 4-amino-2-butyl-isoindole-1,3-dione
• Synonyms: 4-amino-2-butyl-isoindole-1,3-dione
• CAS NO: 6305-66-4
• Molecular Formula: C12H14N2O2
• Molecular Weight: 218.25
• Mol File: 6305-66-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 376.7°C at 760 mmHg
• Flash Point: 181.6°C
• Appearance: /
• Density: 1.243g/cm³
• Vapor Pressure: 7.13E-06mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 4-amino-2-butyl-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-2-butyl-isoindole-1,3-dione(6305-66-4)
• EPA Substance Registry System: 4-amino-2-butyl-isoindole-1,3-dione(6305-66-4)

Safety Data

• Hazardous Substances Data: 6305-66-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H14N2O2/c1-2-3-7-14-11(15)8-5-4-6-9(13)10(8)12(14)16/h4-6H,2-3,7,13H2,1H3

Upstream product

• 54395-36-7 2-butyl-4-nitroisoindoline-1,3-dione 
• 641-70-3 3-nitrophthalic acid anhydride 

Relevant articles and documents

A new 3-hydroxyphthalimide-based turn-on fluorescent probe for Hg2+ detection in aqueous solution

A new 3-hydroxyphthalimide-based turn-on fluorescent probe is designed and synthesized. This probe can be used to determine the presence of Hg2+ ions by fluorescence spectroscope with high selectivity over other metal ions in aqueous solution. The analytical detection limit for Hg2+ is as low as 6.5 × 10?7 M. The recognition mechanism is attributed to Hg2+-promoted carbonothioate group cleavage and a subsequent excited-state intramolecular proton transfer mechanisms.

New phthalimide-methionine dyad-based fluorescence probes for reactive oxygen species: Singlet oxygen, hydrogen peroxide, and hypochlorite

Different reactive oxygen species were detected by the molecular probes 1-3 that were composed of the phthalimide fluorophore as reporter and a methionine-derived thioether side-chain as receptor part. The sulfoxides that were formed as the primary oxidation products show strong fluorescence in the blue-green (430-540?nm) spectral region. Self-sensitized oxidation by singlet oxygen is in general inefficient indicating rapid electron-transfer quenching of the excited probe molecules. With hydrogen peroxide as thermal oxidant conversion to the sulfoxides is slow but can be accelerated by addition of titanium(IV) catalysts, whereas hypochlorite as oxidant behaves much more reactive even under uncatalyzed conditions. Singlet oxygen that is generated by energy transfer from the photosensitizer Rose Bengal was detected by sensor 1a with rate constants of >107M–1?s–1, a typical rate constant for the oxidation of thioethers to sulfoxides.

A selective and sensitive phthalimide-based fluorescent probe for hydrogen sulfide with a large Stokes shift

A phthalimide-based fluorescent probe for hydrogen sulfide has been developed with high sensitivity and excellent selectivity. Upon treatment with hydrogen sulfide, this probe displays a strong fluorescence enhancement (196-fold) with a large Stokes shift (105 nm). Moreover, the potential application of using this probe in biological systems has been demonstrated by imaging hydrogen sulfide in living cells.