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2-{2-[4-(dimethylamino)phenyl]ethenyl}-1,3,3-trimethyl-3H-indolium is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

6307-03-5

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6307-03-5 Usage

Chemical class

Indolium dyes

Molecular structure

Contains a dimethylamino group, a phenyl group, and a double bond

Usage

Commonly used as a fluorescent label in biological and chemical assays

Properties

Strong absorption and emission properties

Applications

Fluorescent imaging, protein labeling, and nucleic acid detection

Suitability

Unique chemical structure makes it suitable for use in fluorescence microscopy, flow cytometry, and high-throughput screening assays.

Check Digit Verification of cas no

The CAS Registry Mumber 6307-03-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,0 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6307-03:
(6*6)+(5*3)+(4*0)+(3*7)+(2*0)+(1*3)=75
75 % 10 = 5
So 6307-03-5 is a valid CAS Registry Number.

6307-03-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name trans-2-<p-(N,N-dimethylamino)styryl>-1',3',3'-trimethylindolium iodide

1.2 Other means of identification

Product number -
Other names 2-[2-(4-Chlor-phenoxy)-aethylamino]-aethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6307-03-5 SDS

6307-03-5Downstream Products

6307-03-5Relevant academic research and scientific papers

A hemicyanine and cucurbit[n]uril inclusion complex: competitive guest binding of cucurbit[7]uril and cucurbit[8]uril

Xu, Weitao,Kan, Jinglan,Redshaw, Carl,Bian, Bing,Fan, Ying,Tao, Zhu,Xiao, Xin

, p. 457 - 465 (2019/06/17)

The interaction between the hemicyanine indole derivative H and the cucubit[n]urils Q[7] and Q[8] has been studied using 1H NMR and UV spectroscopy as well as by fluorescence experiments. Competitive studies on the inclusion of H by Q[7] and Q[

A new ratiometric fluorescence assay based on resonance energy transfer between biomass quantum dots and organic dye for the detection of sulfur dioxide derivatives

Zhao, Jingjin,Peng, Yao,Yang, Keqin,Chen, Yunyun,Zhao, Shulin,Liu, Yi-Ming

, p. 41955 - 41961 (2019/12/28)

Sulfur dioxide (SO2) is considered as the fourth gas signal molecule after nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S). It plays important roles in several physiological processes. Therefore, the design and syn

OFF/ON Red-Emitting Fluorescent Probes for Casein Recognition and Quantification Based on Indolium Derivatives

Yang, Wei,Liu, Chunlin,Gao, Qingyun,Du, Jinya,Shen, Ping,Yang, Changying

, p. 391 - 398 (2017/02/05)

Five derivatives of 2, 3, 3-trimethyl-3H-indolium containing different electron donor groups (H1 - H5) were synthesized for the determination of proteins. H3, a sensitive red-emitting fluorescent probe, was found for the discrimination of hydrophobic prot

A mitochondria-targeted fluorescent probe for ratiometric detection of endogenous sulfur dioxide derivatives in cancer cells

Li, Dong-Peng,Wang, Zhao-Yang,Cao, Xiang-Jian,Cui, Jie,Wang, Xin,Cui, Hao-Zhong,Miao, Jun-Ying,Zhao, Bao-Xiang

supporting information, p. 2760 - 2763 (2016/02/18)

A new mitochondria-targeted fluorescent probe HCy-D, constructed by dansyl and hemicyanine fluorophores, for SO2 derivatives (HSO3-/SO32-) was presented. This probe was designed based on a new FRET platform. HCy-D showed a ratiometric, sensitive and rapid response to HSO3-/SO32-. Importantly, HCy-D was successfully used for fluorescence imaging of endogenous bisulfite in HepG2 cells, which may benefit cancer diagnosis by discriminating liver cancer cells from normal liver cells.

2-Styrylindolium based fluorescent probes visualize neurofibrillary tangles in Alzheimer's disease

Gu, Jiamin,Anumala, Upendra Rao,Lo Monte, Fabio,Kramer, Thomas,Heyny Von Haussen, Roland,Hoelzer, Jana,Goetschy-Meyer, Valerie,Mall, Gerhard,Hilger, Ingrid,Czech, Christian,Schmidt, Boris

, p. 7667 - 7671 (2013/02/22)

We evaluated 2-styrylindolium derivatives (6-11) as novel and selective probes for neurofibrillary tangles (NFTs) on brain sections of AD patients. The staining experiments indicated that these compounds may bind selectively to NFTs in the presence of ss-amyloid (Ass) plaques. Cell free binding assays confirmed that 2-[2-[4-(1-pyrrolidinyl)phenyl]ethenyl]-1,3,3-trimethyl-3H- indolium iodide (9) and 2-[2-[4-(diethylamino)phenyl]ethenyl]-1-butyl-3,3- dimethyl-3H-indolium iodide (11) display excellent affinities to Tau-aggregates (IC50 values of 5.1 and 1.4 nM, respectively) in the displacement of Thiazin Red R. These probes have good solubility in distilled water and low or no cytotoxicity in zebrafish embryo and liver hepatocellular carcinoma cell assays.

The synthesis, structure and spectral properties of new long-wavelength benzodipyrroleninium-based bis-styryl dyes

Fedyunyayeva, Iryna A.,Klochko, Oleksii P.,Semenova, Lga M.,Khabuseva, Sania U.,Povrozin, Yevgen A.,Sokolyk, Oksana O.,Stepanenko, Olena Yu.,Terpetschnig, Ewald A.,Patsenker, Leonid D.

experimental part, p. 201 - 210 (2011/12/15)

Novel bis-styryl dyes based on a quaternized centrosymmetrical benzodipyrrolenine moiety were synthesized by reaction of a quaternized benzodipyrrolenine with two equivalents of 4-dimethylaminobenzaldehyde, 4-dimethylaminocinnamoic aldehyde or 4-(3,5-diph

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