63075-64-9Relevant articles and documents
Synthesis and antiviral activity of new phosphonobutoxypurines
Harnden, Michael R.,Serafinowska, Halina T.
, p. 2215 - 2218 (1996)
A series of new 9-(4-phosphonobutoxy)purines was synthesized and evaluated as antiviral agents. 9-(4-Phosphonobutoxy)guanine displayed potent and selective activity against HIV-1 in peripheral blood lymphocytes.
Glucose compound, medicinal composition and application thereof
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Paragraph 0089; 0167; 0172-0174, (2020/04/06)
The invention discloses a glucose compound, a medicinal composition and application thereof. The glucose compound or pharmaceutically acceptable salt thereof as shown in a formula I almost has no activity of inhibiting cancer cell proliferation in vitro, but has excellent anti-cancer effect and excellent inhibition effect on tumor metastasis in an in-vivo activity test, and has an excellent marketapplication prospect.
Covalent and selective immobilization of GST fusion proteins with fluorophosphonate-based probes
Wang, Xiafeng,Guo, Tianlin,Chen, Jiahui,Li, Xiaofeng,Zhou, Yiqing,Pan, Zhengying
, p. 4661 - 4664 (2018/05/15)
Using GST fusion protein tags is an attractive approach for protein immobilization. Here we report that pyrimidine-based small-molecule probes with a fluorophosphonate reactive group could specifically react with the tyrosine-111 residue of the Schistosom