63085-02-9 Usage
Uses
Used in Pharmaceutical Industry:
(3E)-N-hydroxycholest-5-en-3-imine is used as a potential pharmaceutical candidate for drug development due to its bioactive properties and unique structure. Its hydroxyl group and nitrogen atom may allow for interactions with biological targets, making it a promising compound for the treatment of various diseases and conditions.
Used in Drug Development:
(3E)-N-hydroxycholest-5-en-3-imine is used as a starting material or intermediate in the synthesis of new drugs and therapeutic agents. Its cholesterol-derived structure and functional groups may provide a basis for the development of innovative medications with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 63085-02-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,0,8 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 63085-02:
(7*6)+(6*3)+(5*0)+(4*8)+(3*5)+(2*0)+(1*2)=109
109 % 10 = 9
So 63085-02-9 is a valid CAS Registry Number.
63085-02-9Relevant academic research and scientific papers
SYNTHESE UND ANTITUMORAKTIVITAET VON PLATIN(II)-KOMPLEXEN MIT CHOLESTERINDERIVATEN
Brunner, H.,Sperl, G.
, p. 935 - 944 (2007/10/02)
Low-density-lipoprotein-receptor binding moieties were introduced into Pt(II) complexes in order to facilitate the selective transport into cancer cells.Cholesterol esters of aminoacids and 2,3-diaminopropionic acid were attached to the PtCl2 fragment via their NH2 groups.Steroidal amine and diamine ligands were synthesized and transformed into the corresponding dichloroplatinum(II) complexes.A steroidal carboxylic acid was prepared and coupled with the Pt(NH3)2 fragment.The antitumor activity of the compounds was tested towards the lymphatic P 388 leukemia of the CD2F1 mouse and towards the human mammary carcinoma cell line MDA-MB 231.The Pt(II) complexes gave a maximum growth inhibition of 54percent.
