631090-48-7

Upstream product

• 210563-62-5 (-)-O,21-dihydrocamptothecin 
• 14892-14-9 (2,3,4,5,6-pentafluorophenoxy)-acetic acid 
• 186668-40-6 5-ethyl-5-hydroxy-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione 
• 7689-03-4 camptothecin 
• 54318-62-6 (9-oxo-7-propionyl-9,11-dihidroindolizino[1,2-b]quinolin-8-yl)methyl formate 
• 186668-38-2 tert-butyl 3-hydroxy-3-(3-hydroxymethyl-4-oxo-4,6-dihydroindolixino<1,2-b>quinolin-2-yl)pentanoate 

Relevant academic research and scientific papers

Synthesis and cytotoxicity of novel 20-O-linked homocamptothecin ester derivatives as potent topoisomerase I inhibitors

In an attempt to improve the antitumor activity of homocamptothecins (hCPTs), a series of novel 20-O-linked hCPT ester derivatives were first designed and synthesized based on a synthetic route, by which hCPTs are acylated with different substituted pheno