6312-48-7

Basic information

• Product Name: 2-CHLORO-3-(4-METHYLPIPERAZINO)NAPHTHOQUINONE
• Synonyms: 2-CHLORO-3-(4-METHYLPIPERAZINO)NAPHTHOQUINONE
• CAS NO: 6312-48-7
• Molecular Formula: C₁₅H₁₅ClN₂O₂
• Molecular Weight: 290.74
• Mol File: 6312-48-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 390.6°C at 760 mmHg
• Flash Point: 190.1°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 2.61E-06mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 2-CHLORO-3-(4-METHYLPIPERAZINO)NAPHTHOQUINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-(4-METHYLPIPERAZINO)NAPHTHOQUINONE(6312-48-7)
• EPA Substance Registry System: 2-CHLORO-3-(4-METHYLPIPERAZINO)NAPHTHOQUINONE(6312-48-7)

Safety Data

• Hazardous Substances Data: 6312-48-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H15ClN2O2/c1-17-6-8-18(9-7-17)13-12(16)14(19)10-4-2-3-5-11(10)15(13)20/h2-5H,6-9H2,1H3

Upstream product

• 74-83-9 methyl bromide 
• 104309-89-9 3-chloro-2-(piperazin-1-yl)-1,4-naphthoquinone 
• 109-01-3 1-methyl-piperazine 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 

Relevant articles and documents

Reactions of quinones with some amino alcohols, thiols and a UV-Vis study

In the present study, the reactions of 2,3-dichloro-1,4-naphthoquinone (DCNQ) with amino-1,2-propanediol and some thiols were investigated. Novel N-, N,S-, and S,O- substituted derivatives were obtained and the structures of all compounds were characteriz

NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.

'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents

2-Chloro-3-(4-methylpiperazin-1-yl)naphthalene-1,4-dione (3a), 2-chloro-3-(pyrrolidin-1-yl)naphthalene-1,4-dione (3b), 2-chloro-3-(piperidin-1-yl)naphthalene-1,4-dione (3c), 2-chloro-3-morpholinonaphthalene-1,4-dione (3d), 2-chloro-3-(2-phenylhydrazinyl)n