63139-97-9

Basic information

• Product Name: (2-METHYL-1,3-THIAZOL-5-YL)METHYLAMINE
• Synonyms: (2-METHYL-1,3-THIAZOL-5-YL)METHYLAMINE;(2-Methylthiazol-5-yl)MethanaMine;C-(2-Methyl-thiazol-5-yl)-methylamine;(2-Methyl-1,3-thiazol-5-yl)methanamine
• CAS NO: 63139-97-9
• Molecular Formula: C₅H₈N₂S
• Molecular Weight: 128.2
• Mol File: 63139-97-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 221.4±15.0 °C(Predicted)
• Appearance: /
• Density: 1.182±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.26±0.29(Predicted)
• CAS DataBase Reference: (2-METHYL-1,3-THIAZOL-5-YL)METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYL-1,3-THIAZOL-5-YL)METHYLAMINE(63139-97-9)
• EPA Substance Registry System: (2-METHYL-1,3-THIAZOL-5-YL)METHYLAMINE(63139-97-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• Hazardous Substances Data: 63139-97-9(Hazardous Substances Data)

Usage

Description

(2-Methyl-1,3-thiazol-5-yl)methylamine is a simple, organic compound composed of various elements such as carbon, hydrogen, nitrogen, and sulfur. It is known for its role in organic synthesis, with a chemical structure that features a thiazole ring, a five-membered aromatic ring containing two non-adjacent heteroatoms (sulfur and nitrogen), to which an amine functional group is attached. Like other amines, this compound has a lone pair of electrons on the nitrogen, allowing it to participate in various chemical reactions.

Uses

Used in Pharmaceutical Industry:
(2-Methyl-1,3-thiazol-5-yl)methylamine is used as a building block or intermediate for drug synthesis, particularly due to its potential for substituent variability and its biological relevance. Its unique structure and reactivity make it a valuable component in the development of new pharmaceutical compounds.
Used in Organic Synthesis:
(2-Methyl-1,3-thiazol-5-yl)methylamine is used as a reagent in various organic synthesis processes, where its thiazole ring and amine functional group can be utilized to form a wide range of chemical products. Its versatility in reactions makes it a useful tool in the synthesis of complex organic molecules.
It is important to handle (2-Methyl-1,3-thiazol-5-yl)methylamine with care, using appropriate safety measures to avoid exposure and potential harm, as with all chemicals.

Upstream product

• 1000686-12-3 5-(azidomethyl)-2-methylthiazole 
• 63140-11-4 2-methyl-5-thiazolylmethyl chloride 
• 56012-38-5 5-(hydroxymethyl)-2-methylthiazole 
• 79836-78-5 ethyl 2-methylthiazole-5-carboxylate 
• 838892-96-9 2-(2-methylthiazol-5-ylmethyl)isoindole-1,3-dione 

Downstream Products

• 1072806-59-7 (2-methylthiazol-5-yl)methanamine hydrochloride 
• 1945950-21-9 PDD00017273 
• 1072804-37-5 2-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-((2-methylthiazol-5-yl)methyl)thiazole-5-carboxamide 

Relevant articles and documents

HEPATITIS B CORE PROTEIN MODULATORS

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula: