63148-57-2 Usage
Description
Poly(methylhydrosiloxane) is a reducing agent. For example, it can
be used for the reduction of esters to alcohols as well as the
reduction of aldehydes and ketone. It can also be used for the
reduction of phosphine oxides to phosphine. Recent study has also
used it for conjugate reduction of α, β-Unsaturated Carbonyl and
Carboxyl Compounds. Finally, it is also used in greener amine
synthesis mediated by reductive amination which is an alternative to
borohydrides.
Chemical Properties
Colorless liquid
Uses
Polymethylhydrosiloxane(PMHS) is an easily handled,inexpensive,non-toxic,and mild reducing agent. PMHS is attractive as a substitute for more expensive or hazardous silanes or siloxanes and as the stoichiometric reductant in catalytic organotin-mediated processes.
It can be cross linked by metal catalyst at low temperature to form waterproof membrane. It is used as waterproof agent of textile, glass, pottery, paper, leather, metal, cement and marble etc, especially in textile waterproof. It is used as insulator and cross linker of paper.
Poly(methylhydrosiloxane) is used in the reduction of esters to alcohols, catalyzed by a combination of titanocene dichloride and either n-BuLi or EtMgBr. It is a safer alternative to triethoxysilane, B22063, for reduction of phosphine oxides to phosphines, catalyzed by Ti(O-i-Pr)4. It is also used in greener amine synthesis by reductive amination as an alternative to borohydrides.
General Description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is an environmentally benign reducing agent and has been enhanced for catalytic efficiency. Click here for more information.Harnessing the reactivity of poly(methylhydrosiloxane) for the reduction and cyclization of biomass to high-value products
References
https://www.alfa.com/en/catalog/L14561/
http://www.sigmaaldrich.com/catalog/product/aldrich/176206? lang=en?ion=US
Wang, Zhigang, A. E. W. ?. And, and J. G. Verkade. "P (MeNCH2CH2)3N:? An Efficient Promoter for the Reduction of Aldehydes and Ketones with Poly (methylhydrosiloxane)." Cheminform 31.7(2000):no-no.
Dfj, Hamstra, et al. "Poly (methylhydrosiloxane) as a green reducing agent in organophosphorus-catalysed amide bond formation." Organic & Biomolecular Chemistry 15.30 (2017).
Kawamorita, Soichiro, et al. "Conjugate Reduction of α, β- Unsaturated Carbonyl and Carboxyl Compounds with Poly (methylhydrosiloxane) Catalyzed by a Silica-Supported Compact Phosphane–Copper Complex."Advanced Synthesis & Catalysis 354.18 (2012):3440-3444.
Check Digit Verification of cas no
The CAS Registry Mumber 63148-57-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,1,4 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 63148-57:
(7*6)+(6*3)+(5*1)+(4*4)+(3*8)+(2*5)+(1*7)=122
122 % 10 = 2
So 63148-57-2 is a valid CAS Registry Number.
