63164-97-6Relevant academic research and scientific papers
Regiochemistry in the Pauson-Khand reaction: Has a trans effect been overlooked?
Robert,Milet,Gimbert,Konya,Greene
, p. 5396 - 5400 (2001)
Alkyne-dicobalt hexacarbonyl complexes have been studied by DFT to examine whether electronic differences in the acetylenic substituents could play a role in determining the regiochemical outcome in the Pauson-Khand reaction. It appears that in some insta
PROTEIN KINASE C AGONISTS
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Paragraph 0299, (2020/09/12)
The present disclosure relates generally to certain diacylglycerol lactone compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by protein kinase C (PKC) agonists, such as HIV.
Nickel-Catalyzed Sonogashira C(sp)-C(sp2) Coupling through Visible-Light Sensitization
Zhu, Da-Liang,Xu, Ruijie,Wu, Qi,Li, Hai-Yan,Lang, Jian-Ping,Li, Hong-Xi
, p. 9201 - 9212 (2020/08/14)
An efficient method for visible-light-initiated, nickel-catalyzed Sonogashira C(sp)-C(sp2) coupling has been developed via an energy-transfer mode. Thioxanthen-9-one as a photosensitizer could significantly accelerate the arylation of alkynes with a wide
Organoaluminum-Mediated Direct Cross-Coupling Reactions
Minami, Hiroki,Saito, Tatsuo,Wang, Chao,Uchiyama, Masanobu
, p. 4665 - 4668 (2015/04/14)
We present a direct cross-coupling reaction between arylaluminum compounds (ArAlMe2·LiCl) and organic halides RX (R=aryl, alkenyl, alkynyl; X=I, Br, and Cl) without any external catalyst. The reaction takes place smoothly, simply upon heating, thereby enabling the efficient and chemo-/stereoselective formation of biaryl, alkene, and alkyne coupling products with broad functional group compatibility.
Synergistic catalysis in the sonogashira coupling reaction: Quantitative kinetic investigation of transmetalation
He, Chuan,Ke, Jie,Xu, Huan,Lei, Aiwen
supporting information, p. 1527 - 1530 (2013/04/24)
Rate-limiting: The transmetalation step of the Sonogashira coupling reaction has been established as the rate-limiting step. This cross-coupling has been demonstrated to be a Pd-catalyzed and Cu-catalyzed synergistic process, which exhibits a first-order
Microwave-promoted hydrogenation and alkynylation reactions with palladium-loaded multi-walled carbon nanotubes
Olivier, Jean-Hubert,Camerel, Franck,Ziessel, Raymond,Retailleau, Pascal,Amadou, Julien,Pham-Huu, Cuong
, p. 920 - 924 (2008/12/20)
Multi-walled carbon nanotubes loaded with Pd(0) clusters (average size distribution 9 nm) have been used under microwave irradiation as catalysts in hydrogenation and alkynylation reactions under "eco-friendly" conditions; reduced cinnamic esters and cross-coupled products were obtained in good yields; use of piperidine as the base provided, in a regiospecific process, novel doubly alkynylated compounds unambiguously characterized by NMR correlation experiments and X-ray diffraction. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.
