631903-03-2Relevant academic research and scientific papers
Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s
Travins, Jeremy M.,Ali, Farah,Huang, Hui,Ballentine, Shelley K.,Khalil, Ehab,Hufnagel, Heather R.,Pan, Wenxi,Gushue, Joan,Leonard, Kristi,Bone, Roger F.,Soll, Richard M.,DesJarlais, Renee L.,Crysler, Carl S.,Ninan, Nisha,Kirkpatrick, Jennifer,Cummings, Maxwell D.,Huebert, Norman,Molloy, Christopher J.,Gaul, Michael,Tomczuk, Bruce E.,Subasinghe, Nalin L.
, p. 1603 - 1606 (2008/12/21)
Complement activation has been implicated in disease states such as hereditary angioedema, ischemia-reperfusion injury, acute respiratory distress syndrome, and acute transplant rejection. Even though the complement cascade provides several protein target
