631917-10-7Relevant academic research and scientific papers
Synthesis of a deep-cavity thiacalix[4]arene
Lhoták, Pavel,?mejkal, Tomá?,Stibor, Ivan,Havlí?ek, Jaroslav,Tkadlecová, Marcela,Pet?í?ková, Hana
, p. 8093 - 8097 (2003)
A novel thiacalix[4]arene derivative bearing four phenyl groups on the upper rim was prepared by the direct condensation of biphenyl-4-ol with elemental sulphur. As revealed by X-ray diffraction analysis, this compound adopts the cone conformation in the solid state, thus creating a cavity with an extended π-aromatic system potentially applicable for solid-state inclusion of suitable molecules. Subsequent alkylation (RI/K2CO 3/acetone, R=Me, Et, Pr) yielded tetraalkylated derivatives, which were studied for their conformational preferences using 1H NMR spectroscopy. While the Me or Et derivatives are conformationally mobile and exhibit thermodynamic equilibria of several conformers in solution (CDCl 3 or CD2Cl2), the corresponding propoxy derivative is infinitely stable at room temperature.
Synthesis of thia-calix[4]arene hydroxamic acids by microwave irradiation
Agrawal,Pancholi
, p. 2446 - 2458 (2008/09/21)
Thia-calix[4]arene hydroxamic acids have been synthesized by partial reduction of nitro-thia-calix[4]arenes with hydrazine hydrate, Rn/Ni, and their coupling with benzoyl chloride under the influence of microwave irradiation with 90-95% yield and 3-6 min
