63200-55-5 Usage
Uses
Used in Pharmaceutical Industry:
2-CHLORO-N-(PHENYLMETHYL)-5H-PYRROLO[3,2-D]PYRIMIDIN-4-AMINE is utilized as a precursor compound for the synthesis of new drugs, specifically targeting the development of anti-cancer and anti-inflammatory agents. Its unique structure allows for the exploration of its potential in modulating biological pathways associated with these conditions, offering a promising avenue for therapeutic intervention.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 2-CHLORO-N-(PHENYLMETHYL)-5H-PYRROLO[3,2-D]PYRIMIDIN-4-AMINE serves as a valuable research tool. It aids scientists in understanding the molecular mechanisms of action and in the design of more effective and targeted pharmaceuticals, potentially leading to breakthroughs in the treatment of various diseases.
Used in Drug Discovery:
2-CHLORO-N-(PHENYLMETHYL)-5H-PYRROLO[3,2-D]PYRIMIDIN-4-AMINE is employed in drug discovery processes to identify and optimize lead compounds with potential therapeutic activity. Its unique chemical properties make it a candidate for further investigation and modification to improve its efficacy, selectivity, and safety profile in treating specific medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 63200-55-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,2,0 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 63200-55:
(7*6)+(6*3)+(5*2)+(4*0)+(3*0)+(2*5)+(1*5)=85
85 % 10 = 5
So 63200-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H11ClN4/c14-13-17-10-6-7-15-11(10)12(18-13)16-8-9-4-2-1-3-5-9/h1-7,15H,8H2,(H,16,17,18)
63200-55-5Relevant academic research and scientific papers
A facile synthesis of 9-deaza analogue of olomoucine
Capek, Petr,Otmar, Miroslav,Masojidkova, Milena,Votruba, Ivan,Holy, Antonin
, p. 779 - 791 (2007/10/03)
Heating of 6-(benzylamino)-2-chloro-9-deazapurine (3) with ethanolamine afforded 6-(benzylamino)-2-[(2-hydroxyethyl)amino]-9-deazapurine (8). Its treatment with formaldehyde in alkaline solution, after protection of the OH group with DMTr, led to hydroxymethylation at position 9. Conversion of the hydroxymethyl group to methyl was performed by catalytic hydrogenation under simultaneous deprotection, which resulted in the formation of the 9-deaza analogue 1 of olomoucine. Compound 1 does not exhibit any significant in vitro cell growth inhibition of CCRF-CEM, HeLa and L-1210 cell lines. Cytostatic activity was found in 6-(benzylamino)-9-deazapurine (2) and its 2-chloro derivative 3 in CCRF-CEM cells with IC50 13.3 and 15:8 μM, respectively.
