63221-68-1

Basic information

• Product Name: pyridoxal phosphate gamma-aminobutyric acid
• Synonyms: pyridoxal phosphate gamma-aminobutyric acid
• CAS NO: 63221-68-1
• Molecular Formula: C₁₂H₁₇N₂O₇P
• Molecular Weight: 332.25
• Mol File: 63221-68-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 596.8°C at 760 mmHg
• Flash Point: 314.7°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 8.75E-16mmHg at 25°C
• Refractive Index: 1.605
• PKA: 1.52±0.10(Predicted)
• CAS DataBase Reference: pyridoxal phosphate gamma-aminobutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: pyridoxal phosphate gamma-aminobutyric acid(63221-68-1)
• EPA Substance Registry System: pyridoxal phosphate gamma-aminobutyric acid(63221-68-1)

Safety Data

• Hazardous Substances Data: 63221-68-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H17N2O7P/c1-8-12(17)10(6-13-4-2-3-11(15)16)9(5-14-8)7-21-22(18,19)20/h5-6,13H,2-4,7H2,1H3,(H,15,16)(H2,18,19,20)/b10-6+

Upstream product

• 54-47-7 pyridoxal 5'-phosphate 
• 56-12-2 4-amino-n-butyric acid 
• 62518-44-9 γ-aminobutyric acid potassium salt 

Downstream Products

• 54-47-7 pyridoxal 5'-phosphate 
• 56-12-2 4-amino-n-butyric acid 

Relevant articles and documents

Schiff's Bases Formed between Pyridoxal 5'-Phosphate and 4-Aminobutanoic Acid. Kinetic and Thermodynamic Study

The overall and individual kinetic constants of formation (k1 and k1i) and hydrolysis (k2, kOH and k2i) of the Schiff's bases formed between pyridoxal 5'-phosphate (PLP) and 4-aminobutanoic acid (GABA) at 10, 20, 25, 30, and 37 deg C, a variable pH and a constant ionic strength of 0.1 M (1 M = 1 mol dm-3) were determined. The formation of a Schiff's base is an intramolecular acid-catalyzed process. The activation and thermodynamic parameters for the formation and hydrolysis of the Schiff's bases were also determined. ΔH and ΔS for the individual processes were all found to be negative.