POKEWEED MITOGEN is a natural substance extracted from the pokeweed plant, which has the ability to stimulate the proliferation of lymphocytes and activate immune cells. It is commonly used in various biological and medical applications due to its immunostimulatory properties.
63231-57-2
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Basic information
- Product Name: POKEWEED MITOGEN
- Synonyms: PHYTOLACCA AMERICANA AGGLUTININ;PHYTOLACCA AMERICANA LECTIN;PHYTOLACCA AMERICANA MITOGEN;POKEWEED MITOGEN;PWM;mitogens,pokeweed;LECTIN FROM PHYTOLACCA AMERICANA*STERILE FILTERED;LECTIN FROM PHYTOLACCA AMERICANA CELL*CU LTURE TESTE
- CAS NO:63231-57-2
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /lyophilized powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: PBS: 1 mg/mL
- CAS DataBase Reference: POKEWEED MITOGEN(CAS DataBase Reference)
- NIST Chemistry Reference: POKEWEED MITOGEN(63231-57-2)
- EPA Substance Registry System: POKEWEED MITOGEN(63231-57-2)
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Safety Data
- Hazard Codes: Xn
- Statements: 42/43
- Safety Statements: 36
- WGK Germany: 3
- RTECS: PZ3540000
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 63231-57-2(Hazardous Substances Data)
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63231-57-2 Usage
Uses
Used in Immunological Research:POKEWEED MITOGEN is used as a positive control to treat cells for the analysis of lymphocyte proliferation. It stimulates cell culture, allowing researchers to study the immune response and evaluate the effectiveness of various treatments.
Used in Lymphocyte Transformation Assay:
POKEWEED MITOGEN is used in the Lymphocyte Transformation Assay and culture medium. This assay is a laboratory technique used to measure the ability of lymphocytes to transform and proliferate in response to an antigen or mitogen, providing valuable information about the immune system's response to specific stimuli.
Used in Activation of CD4+ T Cells:
POKEWEED MITOGEN is used for the stimulation of cluster of differentiation (CD4+) T cells. CD4+ T cells, also known as T helper cells, play a crucial role in the immune system by activating other immune cells and orchestrating the immune response.
Used in Activation of Primary Peripheral Blood Lymphocytes:
POKEWEED MITOGEN is used for the activation of primary peripheral blood lymphocytes. This process is essential for understanding the immune system's response to various stimuli and developing new treatments for immune-related disorders.
Used in Stimulation of Peripheral Blood Mononuclear Cells:
POKEWEED MITOGEN is used for the stimulation of peripheral blood mononuclear cells. These cells, which include lymphocytes and monocytes, are critical components of the immune system and play a vital role in the body's defense against infections and diseases.
Biochem/physiol Actions
Lectin agglutinates cells and precipitates polysaccharides and glycoproteins. It has anti-cancer, anti-human immunodeficiency virus (anti-HIV) and anti-microbial infection properties. Lectin is associated with toxic allergens and hemagglutinins. Lectin inhibits mucosal atrophy, lowers type 2 diabetes and obesity, enhances nutrient absorption and regulates drug targeting.Check Digit Verification of cas no
The CAS Registry Mumber 63231-57-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,2,3 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.Calculate Digit Verification of CAS Registry Number 63231-57:
(7*6)+(6*3)+(5*2)+(4*3)+(3*1)+(2*5)+(1*7)=102
102 % 10 = 2
So 63231-57-2 is a valid CAS Registry Number.
63231-57-2Upstream product
63231-57-2Downstream Products
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POKEWEED MITOGEN
