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• 88-67-5 2-Iodobenzoic acid 
• 136582-33-7 N-(2-bromobenzyl)-2-iodobenzamide 

Relevant academic research and scientific papers

Synthesis of 3-(arylmethylene)isoindolin-1-ones from ynamides by Heck-Suzuki-Miyaura domino reactions. Application to the synthesis of lennoxamine

Substituted 3-(arylmethylene)isoindolin-1-ones can be efficiently synthesized from various ynamides and boronic acids by palladium-catalyzed Heck-Suzuki-Miyaura domino reactions. This methodology has been applied to the total synthesis of lennoxamine and a concise route to this isoindolobenzazepine alkaloid was achieved in eight steps from 2,3-dimethoxybenzoic acid via a key intermediate ynamide.

Heck - Suzuki - Miyaura domino reactions involving ynamides. An efficient access to 3-(arylmethylene)isoindolinones

(Matrix Presented) Substituted 3-(arylmethylene)isoindolin-1-ones can be efficiently synthesized in a stereoselective manner from various ynamides and boronic acids by palladium-catalyzed Heck-Suzuki-Miyaura domino reactions.

Intramolecular Heck reaction of methylenephthalimidine derivatives: A simple route to lennoxamine and chilenine

A new concise route to the key intermediate for isoindolobenazepine alkaloids, lennoxamine and chilenine, was developed using amine and keto-ester condensation followed by Heck reaction.