632356-90-2Relevant academic research and scientific papers
4-Formylazetidin-2-ones, synthon for the facile synthesis of enantiopure 4-aminopiperidin-2-ones
Krishnaswamy, Devanathan,Govande, Vidyesh V.,Deshmukh, Abdul Rakeeb A. S.
, p. 1903 - 1908 (2007/10/03)
Enantiopure 4-formylazetidin-2-ones 1a-d have been used as building blocks for the synthesis of 4-aminopiperidin-2-ones 6a-d in 28-39% overall yields. The synthesis involves ring expansion of azetidinone 4a-d via methanolysis followed by a reductive cycli
