6325-56-0 Usage
Uses
Used in Organic Synthesis:
(E)-1-(4-methoxynaphthalen-1-yl)-2-(3,4,5-trimethoxyphenyl)diazene is used as an intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-1-(4-methoxynaphthalen-1-yl)-2-(3,4,5-trimethoxyphenyl)diazene is used as a key compound in the development of new drugs. Its specific structural features and reactivity make it a promising candidate for the design and synthesis of novel therapeutic agents, potentially targeting a wide range of medical conditions.
Used in Chemical Research:
(E)-1-(4-methoxynaphthalen-1-yl)-2-(3,4,5-trimethoxyphenyl)diazene is also utilized in chemical research to study the properties and reactivity of diazenes and related compounds. This helps scientists gain a deeper understanding of the underlying chemical principles and mechanisms, which can lead to the discovery of new applications and advancements in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 6325-56-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,2 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6325-56:
(6*6)+(5*3)+(4*2)+(3*5)+(2*5)+(1*6)=90
90 % 10 = 0
So 6325-56-0 is a valid CAS Registry Number.
6325-56-0Relevant academic research and scientific papers
Photoresponsive azo-combretastatin A-4 analogues
Rastogi, Shiva K.,Zhao, Zhenze,Barrett, Scott L.,Shelton, Spencer D.,Zafferani, Martina,Anderson, Hailee E.,Blumenthal, Madeleine O.,Jones, Lindsey R.,Wang, Lei,Li, Xiaopeng,Streu, Craig N.,Du, Liqin,Brittain, William J.
, p. 1 - 7 (2017/11/24)
Colchicine analogues in which an azo group is incorporated into a molecule containing the key pharmacophore of colchicine, have found particular utility as switchable tubulin binding chemotherapeutics. Combretastatin is a related compound containing a stilbene fragment that shows different bioactivity for the cis and trans isomers. We have performed cell assays on 17 new compounds structurally related to a previously reported azo-analogue of combretastatin. One of these compounds showed enhanced potency against HeLa (IC50 = 0.11 μM) and H157 cells (IC50 = 0.20 μM) for cell studies under 400 nm irradiation and the highest photoactivity (IC50 with irradiation/IC50 in dark = 550). We have performed docking and physicochemical studies of this new compound (7). Kinetic studies in water reveal a longer half-life for the cis isomer of 7 which may be one factor responsible for the better IC50 values in cell assays and the improved photoresponsive behavior.
