63254-90-0Relevant academic research and scientific papers
A new laccase-catalyzed domino process and its application to the efficient synthesis of 2-aryl-1H-benzimidazoles
Leutbecher, Heiko,Constantin, Mihaela-Anca,Mika, Sabine,Conrad, Jürgen,Beifuss, Uwe
experimental part, p. 605 - 608 (2011/03/18)
The laccase-catalyzed domino reaction of o-phenylenediamine and benzaldehydes with aerial oxygen as the oxidant exclusively yields 2-aryl-1H-benzimidazoles in good to very good yields. It is easy to perform under very mild reaction conditions.
