63257-86-3Relevant academic research and scientific papers
Ruthenium-Catalyzed [2 + 2 + 2] Cycloaddition Reaction Forming 2-Aminopyridine Derivatives from α,ω-Diynes and Cyanamides
Ye, Fei,Haddad, Mansour,Ratovelomanana-Vidal, Virginie,Michelet, Véronique
supporting information, p. 1104 - 1107 (2017/03/14)
A novel, efficient, and mild synthetic route for the preparation of 2-aminopyridines via ruthenium-mediated [2 + 2 + 2] cycloaddition of α,ω-diynes and cyanamides has been developed. This atom-economical catalytic process demonstrated remarkable regioselectivities to access pyridine derivatives of high synthetic utility.
