6326-74-5 Usage
Uses
Given the limited information available, the following uses are speculative and based on the compound's potential for pharmacological applications:
Used in Pharmaceutical Research:
AKOS B018327 is used as a research compound for exploring its interactions with biological systems, particularly within the central nervous system, to understand its potential therapeutic effects and mechanisms of action.
Used in Drug Development:
In the pharmaceutical industry, AKOS B018327 is utilized as a candidate molecule in the development of new drugs, possibly targeting conditions related to the central nervous system or other biological processes where its effects could be beneficial.
Check Digit Verification of cas no
The CAS Registry Mumber 6326-74-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,2 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6326-74:
(6*6)+(5*3)+(4*2)+(3*6)+(2*7)+(1*4)=95
95 % 10 = 5
So 6326-74-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO3S2/c1-15-8-4-3-7(5-9(8)16-2)6-10-11(14)13-12(17)18-10/h3-6H,1-2H3,(H,13,14,17)/b10-6+
6326-74-5Relevant academic research and scientific papers
Introducing broadened antibacterial activity to rhodanine derivatives targeting enoyl-acyl carrier protein reductase
Sun, Zhi-Gang,Xu, Yun-Jie,Xu, Jian-Fei,Liu, Qi-Xing,Yang, Yu-Shun,Zhu, Hai-Liang
, p. 125 - 129 (2019/03/28)
Broadened antibacterial activity was introduced to rhodanine derivatives targeting Mycobacterial tuberculosis enoyl-acyl carrier protein reductase (Mtb InhA) by recruiting feature of xacins to bring DNA Gyrase B inhibitory capability. This is significant for preventing further bacterial injections in the tuberculosis treatment. The most potent compound Cy14 suggested comparable bioactivity (IC50=3.18μM for Mtb InhA; IC50=10nM for DNA Gyrase B) with positive controls. Structure–activity relationship discussion and molecular docking model revealed the significance of rhodanine moiety and derived methoxyl on meta-position, pointing out orientations for future modification.
