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63261-04-1

1H-Benzimidazol-2-amine, 1-(1-phenylethyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 63261-04-1 Structure

  • Basic information

    1. Product Name: 1H-Benzimidazol-2-amine, 1-(1-phenylethyl)-
    2. Synonyms:
    3. CAS NO:63261-04-1
    4. Molecular Formula: C15H15N3
    5. Molecular Weight: 237.304
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 63261-04-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1H-Benzimidazol-2-amine, 1-(1-phenylethyl)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1H-Benzimidazol-2-amine, 1-(1-phenylethyl)-(63261-04-1)
    11. EPA Substance Registry System: 1H-Benzimidazol-2-amine, 1-(1-phenylethyl)-(63261-04-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 63261-04-1(Hazardous Substances Data)

63261-04-1 Usage

Structure

Benzimidazole derivative with an amine group and a phenylethyl substituent

Usage

Building block in the synthesis of pharmaceutical drugs and other organic compounds

Potential activities

Biological and pharmacological activities due to its structural features

Possible applications

Development of new medications or research studies, but may vary depending on the context and specific compounds created.

Check Digit Verification of cas no

The CAS Registry Mumber 63261-04-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,2,6 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 63261-04:
(7*6)+(6*3)+(5*2)+(4*6)+(3*1)+(2*0)+(1*4)=101
101 % 10 = 1
So 63261-04-1 is a valid CAS Registry Number.

63261-04-1Relevant articles and documents

Synthesis, in vitro antiplatelet activity and molecular modelling studies of 10-substituted 2-(1-piperazinyl)pyrimido[1,2-a]benzimidazol-4(10H)-ones

Di Braccio, Mario,Grossi, Giancarlo,Signorello, Maria Grazia,Leoncini, Giuliana,Cichero, Elena,Fossa, Paola,Alfei, Silvana,Damonte, Gianluca

, p. 564 - 578 (2013)

The multistep preparation of the new 10-substituted 2-(1-piperazinyl) pyrimido[1,2-a]benzimidazol-4(10H)-ones 6a-o, and of the two isomers 10-ethyl-2-(diethylamino)pyrimido[1,2-a]benzimidazol-4(10H)-one 6p and 10-ethyl-4-(diethylamino)pyrimido[1,2-a]benzimidazol-2(10H)-one 13, as well as the in vitro evaluation of their inhibitory activity on human platelet aggregation induced in platelet-rich plasma by ADP, collagen or the Ca 2+ ionophore A23187 were here described. Nine out of fifteen 2-(1-piperazinyl)derivatives (6g-o) showed good inhibitory properties towards all the platelet aggregation agonists used. Moreover, a molecular modelling study has been performed on two of the best compounds of this series (6i and 6o) to confirm in silico their interactions with the catalytic site of human platelet PDE3, using the X-ray data of the PDE3B isoform in complex with an inhibitor.

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