6327-16-8

Basic information

• Product Name: 2-amino-7-ethyl-6-methylpyrido[2,3-d]pyrimidine-4(1H)-thione
• CAS NO: 6327-16-8
• Molecular Formula: C₁₀H₁₂N₄S
• Molecular Weight: 220.2941
• Mol File: 6327-16-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 410.7°C at 760 mmHg
• Flash Point: 202.2°C
• Density: 1.42g/cm³
• Vapor Pressure: 5.92E-07mmHg at 25°C
• Refractive Index: 1.728
• CAS DataBase Reference: 2-amino-7-ethyl-6-methylpyrido[2,3-d]pyrimidine-4(1H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-7-ethyl-6-methylpyrido[2,3-d]pyrimidine-4(1H)-thione(6327-16-8)
• EPA Substance Registry System: 2-amino-7-ethyl-6-methylpyrido[2,3-d]pyrimidine-4(1H)-thione(6327-16-8)

Safety Data

• Hazardous Substances Data: 6327-16-8(Hazardous Substances Data)

Usage

Main Properties

1. Chemical Name: 2-amino-7-ethyl-6-methylpyrido[2,3-d]pyrimidine-4(1H)-thione
2. Common Name: AMPT
3. Chemical Structure: Heterocyclic compound with a pyrido-pyrimidone core structure
4. Function: Selective inhibitor of tryptophan hydroxylase
5. Application: Used in neuroscience research
6. Role: Investigates serotonin's role in physiological and behavioral processes
7. Therapeutic Use: Studied for the treatment of psychiatric disorders like depression and anxiety

Chemical Structure

Contains an amino group (2-amino)
Ethyl (7-ethyl) and methyl (6-methyl) substituents
Pyrido[2,3-d]pyrimidine core structure
Thione functional group (pyrido[2,3-d]pyrimidine-4(1H)-thione)

Functionality

Acts as a potent and specific inhibitor of tryptophan hydroxylase
Inhibits the rate-limiting step in serotonin synthesis

Application in Research

Utilized to study serotonin's role in various physiological and behavioral processes
Investigates the potential therapeutic interventions related to serotonin

Therapeutic Potential

Investigated for its efficacy in treating psychiatric disorders like depression and anxiety
Offers insights into the modulation of serotonin levels in the brain

In summary, AMPT, also known as 2-amino-7-ethyl-6-methylpyrido[2,3-d]pyrimidine-4(1H)-thione, is a compound with significant implications in neuroscience research, particularly in understanding serotonin's function and potential therapeutic applications in psychiatric disorders. Its unique chemical structure and inhibitory properties make it a valuable tool in studying serotonin pathways and developing interventions for related conditions.