63272-39-9

Basic information

• Product Name: Benzamide, N-(1-methylene-2-oxopropyl)-
• CAS NO: 63272-39-9
• Molecular Formula: C11H11NO2
• Molecular Weight: 189.214
• Mol File: 63272-39-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(1-methylene-2-oxopropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(1-methylene-2-oxopropyl)-(63272-39-9)
• EPA Substance Registry System: Benzamide, N-(1-methylene-2-oxopropyl)-(63272-39-9)

Safety Data

• Hazardous Substances Data: 63272-39-9(Hazardous Substances Data)

Upstream product

• 93204-46-7 N-benzoyl-AlaCH₂Cl 

Relevant articles and documents

Iron-catalysed 1,2-acyl migration of tertiary α-azido ketones and 2-azido-1,3-dicarbonyl compounds

Iron-catalysed 1,2-acyl migration of tertiary α-azido ketones and 2-azido-1,3-dicarbonyl compounds provides a simple and atom-economical approach toward enamides and isoquinolones. This paper reports two catalyst systems for these transformations which employ iron(ii) complexes [Fe(dpbz)]Br2 (dpbz = 1,2-bis(diphenylphosphino)benzene) and FeBr2/Et3N, respectively. [Fe(dpbz)]Br2 was found to be highly effective at converting 2-azido-2,3-dihydro-1H-inden-1-ones to isoquinolones. The reagent combination of FeBr2/Et3N, on the other hand, exhibited a broader catalytic scope, owing to the beneficial effect of Et3N. This latter catalyst system enables 2-azido-2-methyl-1,3-dicarbonyl compounds to be converted to the corresponding enamides under mild conditions in good yields.