63276-44-8Relevant articles and documents
MODIFIED MACROMOLECULE
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Page/Page column 110-111; 22/28, (2008/06/13)
The present invention relates to a macromolecule having a controlled terminal group stoichiometry, the macromolecule including a surface layer, at least one subsurface layer and at least two terminal groups including: a first terminal group which is a res
Solution-phase synthesis of an anti-human immunodeficiency virus peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), and the modification of Trp by the p-methoxybenzyl group of cys during trimethylsilyl trifluoromethanesulfonate deprotec
Tamamura,Otaka,Takada,Terakawa,Yoshizawa,Masuda,Ibuka,Murakami,Nakashima,Waki,Matsumoto,Yamamoto,Fujii
, p. 12 - 18 (2007/10/02)
T22 ([Tyr5,12, Lys7]-polyphemusin II) was previously synthesized by a solid-phase method and was found to have a strong anti-human immunodeficiency virus (HIV) activity, comparable to that of 3'-azido-2',3'-dideoxy- thymidine (AZT).
Synthesis of a Cyclic Peptide Polyamine: A Comparative Study of Routes to Cyclo-(Lys-Lys-Gly)2
Bailey, Patrick D.,Crofts, Gavin A.
, p. 3207 - 3210 (2007/10/02)
Several methods for the preparation of cyclo-(Lys-Lys-Gly)2 were compared.Cyclisation of linear hexapeptides of the type H-2-X was most efficient using excess DPPA with the free amino acid (i.e.X = OH), but purification and scale-up wer