63277-59-8Relevant academic research and scientific papers
Neuroleptic Activity in 5-Aryltetrahydro-γ-carbolines
Harbert, Charles A.,Plattner, Jacob J.,Welch, Willard M.,Weissman, Albert,Koe, B. Kenneth
, p. 635 - 643 (2007/10/02)
A series of 5-aryltetrahydro-γ-carbolines was prepared by a novel N-arylation procedure and tested for neuroleptic activity in a rat antiamphetamine model.The systematic exploration of structural parameters leading to 8-fluoro-5-(4-fluorophenyl)-2-4-hydr
Process for preparing indole derivatives
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, (2008/06/13)
Certain indole derivatives, and especially certain 1,2,3,4-tetrahydrocarbazoles, 1,2,3,4-tetrahydro-γ-carbolines and 1,2,3,4-tetrahydropyrrolo-[3,4-b]indoles are prepared by reacting the appropriate phenylhydrazine salt and ketone in the presence of a weakly basic solvent such as pyridine, quinoline, N,N-dimethylaniline, picoline or lutidine at a temperature in the range of about 50° to 180° C.
