63316-22-3

Upstream product

• 52499-94-2 2,3,4,5,6-pentamethylbenzenesulfonyl chloride 
• 700-12-9 pentamethylbenzene, 

Downstream Products

• 96863-40-0 2-Methoxymethyl-3,4,5,6-tetramethyl-benzenesulfonyl fluoride 
• 96863-39-7 3-Methoxymethyl-2,4,5,6-tetramethyl-benzenesulfonyl fluoride 
• 111895-20-6 2,3,4,5-Tetramethyl-6-nitromethyl-benzenesulfonyl fluoride 
• 111895-21-7 2,3,4,5-Tetramethyl-6-nitrooxymethyl-benzenesulfonyl fluoride 
• 87589-12-6 6-Methoxymethyl-4,5,7-trimethyl-3H-benzo[c][1,2]oxathiole 1,1-dioxide 
• 87570-13-6 3,5-Bis-methoxymethyl-2,4,6-trimethyl-benzenesulfonyl fluoride 
• 95118-24-4 3-Hydroxymethyl-2,4,5,6-tetramethyl-benzenesulfonyl fluoride 

Relevant academic research and scientific papers

Synthesis of 17-(isocyanotosylmethylene) steroids: precursors to pregnane derivatives

The synthesis is described of a series of twenty 17-(isocyanotosylmethylene) steroids 5 from 17-oxo steroids and 4-tolylsulfonylmethyl isocyanide (TosMIC).Furthermore, nine analogous 17-(isocyanosulfonylmethylene) steroids (15-21a) have been prepared usin

OXIDATION OF METHYL-SUBSTITUTED BENZENESULFONYL FLUORIDES IN THE PbO2-HSO3F SYSTEM

The transformations of the sulfonyl fluorides of methyl-substituted benzenes in the PbO2-HSO3F system were studied.They take place through a stage involving the one-electron oxidation of the substrate to aromatic radical-cations.One of the transformation paths of the latter is realized through the elimination of a proton from the methyl groups involved to the greatest degree in the delocalization of the unpaired electron.This leads to the formation of diarylmethanes and the fluorosulfonates of substituted benzyl alcohols, which give substituted tolylsultones and benzyl alcohols during hydrolysis of the acid solution and methyl ethers of benzyl alcohols during methanolysis.The other path, which arises during localization of the unpaired electron in the unsubstituted positions of the benzene ring, leads to biaryls.