633283-63-3

Basic information

• Product Name: 1-N-BOC-4-(2-CHLORO-4-PYRIDINYL) PIPERAZINE
• Synonyms: 1-N-BOC-4-(2-CHLORO-4-PYRIDINYL) PIPERAZINE;tert-butyl 4-(2-chloropyridin-4-yl)piperazine-1-carboxylate;4-(2-Chloro-4-pyridinyl)-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester;1-Piperazinecarboxylic acid, 4-(2-chloro-4-pyridinyl)-, 1,1-dimethylethyl ester
• CAS NO: 633283-63-3
• Molecular Formula: C₁₄H₂₀ClN₃O₂
• Molecular Weight: 297.784
• Mol File: 633283-63-3.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-N-BOC-4-(2-CHLORO-4-PYRIDINYL) PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-BOC-4-(2-CHLORO-4-PYRIDINYL) PIPERAZINE(633283-63-3)
• EPA Substance Registry System: 1-N-BOC-4-(2-CHLORO-4-PYRIDINYL) PIPERAZINE(633283-63-3)

Safety Data

• Hazardous Substances Data: 633283-63-3(Hazardous Substances Data)

Usage

Type of Compound

Piperazine derivative

Protecting Group

Boc (tert-butyloxycarbonyl)

Substituent

2-chloro-4-pyridinyl

Usage

Medicinal chemistry and drug development

Application

Intermediate in the synthesis of pharmaceuticals

Preparation

Used for various bioactive compounds

Potential

Building block for new drugs targeting central nervous system disorders and other medical conditions

Synthesis

Can be used as a starting material for research and development in the pharmaceutical industry

Upstream product

• 73583-37-6 2-chloro-4-bromopyridine 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 26452-80-2 2,4-dichloropyridine 
• 153034-86-7 2-chloro-4-iodopyridine 
• 34941-91-8 2-chloro-4-fluoropyridine 

Downstream Products

• 1143578-17-9 tert-butyl 4-(2-phenylpyridin-4-yl)piperazine-1-carboxylate 
• 1143577-07-4 tert-butyl 4-[2-(2,4-difluorophenyl)pyridin-4-yl]piperazine-1-carboxylate 
• 1143577-09-6 1-[2-(2,4-difluorophenyl)pyridin-4-yl]piperazine 
• 1143577-13-2 4-[2-(2,4-difluorophenyl)pyridin-4-yl]-N-(pyridazin-3-yl)piperazine-1-carboxamide 
• 1296885-72-7 C₂₄H₃₂ClN₅O 
• 1296885-71-6 C₂₂H₂₉ClN₄O₂ 

Relevant articles and documents

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

2-AMINOTHIAZOLE DERIVATIVE OR SALT THEREOF

[Problem] To provide a compound useful as an active ingredient in a pharmaceutical composition for treating bladder storage disorders, dysuria, lower urinary tract diseases, and the like. [Solution] The inventors of the present invention have discovered that a 2-aminothiazole derivative exhibits an excellent muscarinic M3 receptor positive allosteric modulator activity, and has potential as a preventative or therapeutic agent against bladder and urinary tract diseases to which bladder contraction mediated by muscarinic M3 receptors contributes. The 2-aminothiazole derivative or salt thereof has potential as a preventative or therapeutic agent against bladder and urinary tract diseases such as, for example, dysuria including underactive bladder, and to which bladder contraction mediated by muscarinic M3 receptors contributes.

Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors

A series of piperazine ureas were designed, synthesized, and evaluated for their potential as novel orally efficacious fatty acid amide hydrolase (FAAH) inhibitors for the treatment of neuropathic and inflammatory pain. We carried out an optimization stud