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(5-methyl-4-nitroso-2-propan-2-yl-phenyl) N,N-bis(2-chloroethyl)carbamate, also known as carmustine, is a nitrosourea alkylating agent with antineoplastic activity. It is a synthetic compound that possesses the ability to inhibit DNA synthesis and function, leading to the death of rapidly dividing cancer cells.
Used in Oncology:
(5-methyl-4-nitroso-2-propan-2-yl-phenyl) N,N-bis(2-chloroethyl)carbamate is used as an antineoplastic agent for the treatment of various types of cancer, including brain tumors, multiple myeloma, and Hodgkin's disease. Its alkylating properties enable it to cross the blood-brain barrier, making it particularly effective against brain tumors.
Used in Combination Chemotherapy:
(5-methyl-4-nitroso-2-propan-2-yl-phenyl) N,N-bis(2-chloroethyl)carbamate is used as a component of combination chemotherapy regimens to enhance the effectiveness of cancer treatment. It is often administered alongside other chemotherapy drugs to maximize the therapeutic impact on cancer cells while minimizing potential side effects.
However, due to its alkylating properties, (5-methyl-4-nitroso-2-propan-2-yl-phenyl) N,N-bis(2-chloroethyl)carbamate can also cause damage to healthy cells, resulting in certain side effects such as bone marrow suppression, nausea, vomiting, and hair loss. It is administered intravenously and must be handled with care due to its potential toxicity.

6333-64-8

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6333-64-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6333-64-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6333-64:
(6*6)+(5*3)+(4*3)+(3*3)+(2*6)+(1*4)=88
88 % 10 = 8
So 6333-64-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H20Cl2N2O3/c1-10(2)12-9-13(18-21)11(3)8-14(12)22-15(20)19(6-4-16)7-5-17/h8-10H,4-7H2,1-3H3

6333-64-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (5-methyl-4-nitroso-2-propan-2-ylphenyl) N,N-bis(2-chloroethyl)carbamate

1.2 Other means of identification

Product number -
Other names 5-methyl-4-nitroso-2-(propan-2-yl)phenyl bis(2-chloroethyl)carbamate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6333-64-8 SDS

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