633336-81-9Relevant academic research and scientific papers
HETEROCYCLYL PYRIMIDINE ANALOGUES AS TYK2 INHIBITORS
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Page/Page column 66, (2014/01/07)
The present invention relates to compounds of formula (I), wherein R, R1, X1 to X5 have the meaning as cited in the description and the claims. Said compounds are useful as TYK2 inhibitors for the treatment or prophylaxis
IMMEDIATE RELEASE PHARMACEUTICAL FORMULATION
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Page 26-27, (2010/02/04)
According to the present invention there is provided an immediate release pharmaceutical formulation comprising, as active ingredient, a compound of formula (I), wherein R1 represents C?1-2#191 alkyl substituted by one or more fluoro substituen
MODIFIED RELEASE PHARMACEUTICAL FORMULATION
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Page 28-29, (2010/02/04)
A modified release pharmaceutical composition comprising, as active ingredient, a compound of formula (I), wherein R1 represents C?1-2#191 alkyl substituted by one or more fluoro substituents;R2 represents hydrogen, hydroxy, methoxy
PHARMACEUTICAL COMBINATION
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Page 133, (2010/02/04)
There is provided a combination product comprising: (1) a compound of claim 1 in WO 02/44145 or a compound of claim 20 in WO 02/44145 (or derivative thereof)or a pharmaceutically-acceptable derivative thereof; and (1) a compound as defined in claim 1 of WO 01/28992 or (2) a compound of Claim 34 of WO 01/28992 or (3) Compound A or B or C or D (or pharmaceutically-acceptable salts thereof) for use in treating arrhythmia or a coagulation controlled complication thereof.
