6335-97-3Relevant articles and documents
Oxone-sodium nitrite mediated N-nitrosamines formation under mild conditions from secondary amines
Gaur, Pinki,Banerjee, Shaibal
, p. 2270 - 2279 (2019/07/03)
Herein, we report an efficient synthesis of N-nitrosamines from cyclic, aliphatic, benzylic, and aromatic secondary amines via a novel straightforward, efficient, and mild chemical process using sodium nitrite and Oxone in methanol as a solvent at 0–5 °C. The demonstrated methodology accounts well for the parameters like cost-effective, short reaction time, clean and safe handling along with good to excellent yields.