63352-69-2Relevant academic research and scientific papers
Aza-Michael reaction promoted by aqueous sodium carbonate solution
Tang, Xiao-Ji,Yan, Zhao-Lei,Chen, Wen-Liang,Gao, Ya-Ru,Mao, Shuai,Zhang, Yan-Lei,Wang, Yong-Qiang
supporting information, p. 2669 - 2673 (2013/06/05)
A general and efficient aza-Michael reaction promoted by aqueous sodium carbonate solution has been developed. The reaction has complete mono-alkylation selectivity and proceeds with complete chirality retention for chiral amino esters. With a broad substrate scope, a well-common catalyst and simple operation, the catalytic approach provides a facile, practicable, economical, and environmentally benign method for the synthesis of β-amino carbonyl compounds.
Diastereoselective synthesis of 4-hydroxypiperidin-2-ones via Cu(I)-catalyzed reductive aldol cyclization
Hon, Wai Lam,Murray, Gordon J.,Firth, James D.
, p. 5743 - 5746 (2007/10/03)
(Chemical Equation Presented) 4-Hydroxypiperidin-2-ones may be prepared in highly diastereoselective fashion using a Cu(I)-catalyzed reductive aldol cyclization of αβ-unsaturated amides with ketones. Used in combination with proline-catalyzed asymmetric M
Synthesis of Heterocyclic Compounds: Part XXVI - 3,6-Diaryl-3,4-dihydro-1,3,2-oxazaphosphorin-2-oxides
Modak, A. S.,Gogte, V. N.,Tilak, B. D.
, p. 907 - 913 (2007/10/02)
3,4-Dihydro-1,3,2-oxazaphosphorin-2-oxides (4a-r) have been prepared by the interaction of aryl β-aryl/alkylaminoethyl ketones (3a-r) with POCl3/Et3N.Various reactions of these compounds, which represent a new ring system, are reported.Few of these compou
Synthesis and Reactions of 3,6-Diaryl-3,4-dihydro-1,3,2-oxazaphosphorin-2-oxides
Tilak, B. D.,Gogte, V.N.,Modak, A.S.
, p. 414 - 415 (2007/10/02)
Aryl β-arylaminoethyl ketones (1), when reacted with phosphorus oxychloride followed by treatment with triethylamine, afford 3,6-diaryl-2-chloro-3,4-dihydro-1,3,2-oxazaphosphorin-2-oxides (3a-u), a hitherto unreported ring system.The oxazaphosphorin (3q), viz. 2-chloro-3-m-anisyl-6-phenyl-3,4-dihydro-1,3,2-oxazaphosphorin, is converted into 7-methoxy-4-phenylquinoline on keeping.This transformation is specific to 3q since other oxazaphosphorins fail to give the quinoline derivative.
