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4-methyl-N-(4-methylphenyl)piperazine-1-carboxamide is a chemical compound with the molecular formula C13H18N2O. It is a white crystalline solid and is classified as a piperazine derivative, which is a heterocyclic compound containing a six-membered ring with two nitrogen atoms. This specific compound features a methyl group attached to both the piperazine ring and the phenyl ring, with a carboxamide group attached to the piperazine nitrogen. It is known for its potential applications in the pharmaceutical industry, particularly as a building block for the synthesis of various drugs and medicinal compounds. The compound's structure and properties make it a versatile intermediate in organic synthesis, with potential uses in the development of treatments for various medical conditions.

6336-71-6

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6336-71-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6336-71-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6336-71:
(6*6)+(5*3)+(4*3)+(3*6)+(2*7)+(1*1)=96
96 % 10 = 6
So 6336-71-6 is a valid CAS Registry Number.

6336-71-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methyl-N-(4-methylphenyl)piperazine-1-carboxamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6336-71-6 SDS

6336-71-6Downstream Products

6336-71-6Relevant academic research and scientific papers

1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

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Paragraph 2074-2076, (2017/02/28)

The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) in-hibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases, including infectious diseases; neoplasms; endocrine, nutritional and metabolic diseases; mental and be-havioral disorders; neurological diseases; diseases of the eye and adnexa; cardiovascular diseases; respiratory diseases; digestive diseases; diseases of the skin and subcutaneous tissue; diseases of the musculoskeletal system and connective tissue; or congenital malformations, de? formations and chromosomal abnormalities.

Palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate: A practical synthesis of unsymmetrical ureas

Vinogradova, Ekaterina V.,Fors, Brett P.,Buchwald, Stephen L.

supporting information; experimental part, p. 11132 - 11135 (2012/08/28)

An efficient method for palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate is reported. The protocol allows for the synthesis of unsymmetrical N,N'-di- and N,N,N'-trisubstituted ureas in one pot and is tolerant of a wide range of functional groups. Insight into the mechanism of aryl isocyanate formation was gleaned through studies of the transmetalation and reductive elimination steps of the reaction, including the first demonstration of reductive elimination from an arylpalladium isocyanate complex to produce an aryl isocyanate.

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