6338-70-1

Basic information

• Product Name: 3-aminosulfolane
• Synonyms: 3-aminosulfolane;3-thiophenamine,tetrahydro-,1,1-dioxide;n-3-sulfolanylamine
• CAS NO: 6338-70-1
• Molecular Formula: C4H9NO2S
• Molecular Weight: 135.18476
• EINECS: 228-730-7
• Mol File: 6338-70-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 334.9°C at 760 mmHg
• Flash Point: 156.3°C
• Appearance: /
• Vapor Pressure: 0.000124mmHg at 25°C
• CAS DataBase Reference: 3-aminosulfolane(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aminosulfolane(6338-70-1)
• EPA Substance Registry System: 3-aminosulfolane(6338-70-1)

Safety Data

• Hazardous Substances Data: 6338-70-1(Hazardous Substances Data)

Usage

General Description

3-aminosulfolane is a chemical compound that belongs to the class of organic compounds known as aminosulfonyl compounds. It is primarily used in the medical field, particularly in the production of certain drugs. Its IUPAC name is [(3,4-dihydro-1,6-dioxo-4-thia-3-azacyclohept-7-yl)sulfonyl]amine. Due to the presence of nitrogen, sulfur, and oxygen atoms within its structure, 3-aminosulfolane exhibits unique chemical and physical properties including the capability to form hydrogen bonds with other compounds. Usage of this compound should be done carefully considering the potential risks associated with it. Research studies are still ongoing to fully explore the potential applications and any possible associated side-effects of this chemical compound.

InChI:InChI=1/C4H9NO2S/c5-4-1-2-8(6,7)3-4/h4H,1-3,5H2/p+1/t4-/m1/s1

Upstream product

• 77-79-2 3-Sulfolene 

Downstream Products

• 923292-90-4 4-(1,1-Dioxotetrahydrothiophen-3-ylamino)-2-methylsulfanylpyrimidine-5-carboxylic acid (4-fluorophenyl)amide 
• 1089669-65-7 5-[2-(difluoromethyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(1,1-dioxidotetrahydro-3-thienyl)-2-thiophenesulfonamide 
• 1196452-25-1 3-[5-({(1R,2S)-2-[(2,2-difluoropropanoyl)amino]-1-phenylpropyl}oxy)-1H-indazol-1-yl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide 
• 1424996-19-9 C₂₉H₃₂N₂O₅S 
• 1352451-97-8 1-(3-chloropyridin-2-yl)-N-{4-cyano-2-[(1,1-dioxidotetrahydrothiophen-3-yl)carbamoyl]-6-methylphenyl}-3-{[5-(trifluoromethyl)-2H-tetrazol-2-yl]methyl}-1H-pyrazole-5-carboxamide 
• 1344706-35-9 2-hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)-N-(3,3-dioxide-tetrahydrothiophen-3-yl)acetamide 
• 1344706-41-7 (R/S)-2-hydroxy-N-(2-oxo-2-(1,1-dioxide-tetrahydrothiophen-3-ylamino)ethyl)-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)acetamide 
• 1246779-24-7 (1R,3aS,3bS,10aR,10bS,11S,12aS)-7-{3-[(1,1-dioxidotetrahydrothiophen-3-yl)carbamoyl]phenyl}-11-hydroxy-10a,12a-dimethyl-1-(propanoyloxy)-1,2,3,3a,3b,4,5,7,10,10a,10b,11,12,12a-tetradecahydrocyclopenta[5,6]naphtho[1,2-f]indazole-1-carboxylic acid 
• 946385-19-9 3-(4-methoxyphenyl)-9-(1,1-dioxytetrahydrothien-3-yl)-9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin-4-one 

Relevant articles and documents

Synthesis of potassium (1,1-dioxothiolan-3-yl)-dithiocarbamate

A method of synthesizing bioactive potassium (1,1-dioxothiolan-3-yl) dithiocarbamate in high yield and purity is reported.

REACTION OF 3-SULFOLENE WITH LIQUID AMMONIA

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