6339-47-5

Basic information

• Product Name: 2-(2-methyl-1H-indol-3-yl)-1,4-diphenylbutane-1,4-dione
• CAS NO: 6339-47-5
• Molecular Formula: C₂₅H₂₁NO₂
• Molecular Weight: 367.4397
• Mol File: 6339-47-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 604.9°C at 760 mmHg
• Flash Point: 305.7°C
• Density: 1.21g/cm³
• Vapor Pressure: 1.39E-14mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 2-(2-methyl-1H-indol-3-yl)-1,4-diphenylbutane-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methyl-1H-indol-3-yl)-1,4-diphenylbutane-1,4-dione(6339-47-5)
• EPA Substance Registry System: 2-(2-methyl-1H-indol-3-yl)-1,4-diphenylbutane-1,4-dione(6339-47-5)

Safety Data

• Hazardous Substances Data: 6339-47-5(Hazardous Substances Data)

Usage

Class of Compound

Organic compounds, specifically indoles.

Structure

Unique structure containing a butane-1,4-dione and diphenyl group, as well as the indole moiety.

Pharmaceutical Potential

Has been studied for its potential as an anti-inflammatory, immunosuppressive agent, and inhibitor of cancer cell growth.

Antioxidant Properties

Exhibits antioxidant properties, which could potentially be valuable for protecting cells from oxidative damage.

Ongoing Research

Further research into the biological activities and potential medical applications of this compound is ongoing.

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 959-28-4 1,4-diphenylbut-2-ene-1,4-dione 

Relevant articles and documents

Indirect regioselective heteroarylation of indoles through a Friedel-Crafts reaction with (E)-1,4-diaryl-2-buten-1,4-diones

A two-step synthesis of 3-heteroaryl indoles has been developed. The first step of the sequence involves a Friedel-Crafts alkylation of indoles with 1,4-diaryl-2-buten-1,4-diones to give the corresponding indoles bearing a 1,4-dicarbonyl moiety. The reaction is catalyzed by InCl3 and takes place with good yields. Cyclization of the diones under different Paal-Knorr conditions allows to prepare indoles substituted at the C3 position with 3-furanyl, 3-pyrrolyl- and 3-thienyl moieties.