63399-56-4

Upstream product

• 3435-26-5 4-chloro-6-phenylpyrimidine 
• 63399-54-2 7-phenyltetrazolo<1,5-c>pyrimidine 

Downstream Products

• 88236-25-3 [1-(6-Phenyl-pyrimidin-4-yl)-1H-[1,2,3]triazol-4-yl]-methanol 
• 88236-31-1 [3-(6-Phenyl-pyrimidin-4-yl)-3H-[1,2,3]triazol-4-yl]-methanol 
• 88236-17-3 1-(6-Phenyl-pyrimidin-4-yl)-1H-[1,2,3]triazole-4,5-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

2,6-Disubstituted 4-azidopyrimidines: synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy

Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol–1; ΔS = 47—65 J mol–1 К–1; Еa = 93—117 kJ mol–1; lgA = 15.1—18.9. They are dependent on electronic properties of the substituents and the polarity of solvent.

SYNTHESIS OF 2- AND 4-AZIDOPYRIMIDINES CONTAINING AN o-HYDROXYPHENYL GROUP AND THEIR REACTION WITH ACETYLENE DERIVATIVES

2- and 4-Azidopyrimidines that contain a phenyl and (or) o-hydroxyphenyl group were synthesized.Substituted 1-pyrimidyl-1,2,3-triazoles were obtained by the reaction of azidopyrimidines with acetylenes.Mixtures of isomeric 1,4- and 1,5-disubstituted triaz