63399-74-6 Usage
Uses
Used in Pharmaceutical Industry:
(R)-1-(benzyloxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structural features and functional groups. It contributes to the development of new drugs by providing a foundation for the creation of diverse chemical compounds with potential therapeutic effects.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-1-(benzyloxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid is utilized as a valuable building block for the preparation of a wide range of biologically active molecules. Its chiral nature and functional groups enable the synthesis of enantiomerically pure compounds, which are essential for the development of effective and selective drugs.
Used in Research and Development:
(R)-1-(benzyloxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid is also employed in research and development settings to explore its potential applications in various chemical and biological processes. Its unique structure allows scientists to investigate its interactions with other molecules and its role in the synthesis of novel compounds with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 63399-74-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,3,9 and 9 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 63399-74:
(7*6)+(6*3)+(5*3)+(4*9)+(3*9)+(2*7)+(1*4)=156
156 % 10 = 6
So 63399-74-6 is a valid CAS Registry Number.
63399-74-6Relevant academic research and scientific papers
Synthesis of (R)-Boc-2-methylproline via a Memory of Chirality Cyclization. Application to the Synthesis of Veliparib, a Poly(ADP-ribose) Polymerase Inhibitor
Kolaczkowski, Lawrence,Barkalow, Jufang,Barnes, David M.,Haight, Anthony,Pritts, Wayne,Schellinger, Adam
, p. 4837 - 4845 (2019/03/07)
(R)-Boc-2-methylproline (3a) was synthesized in good yield with excellent stereochemical control from alanine benzyl ester hydrochloride 11. The process, which is based on a modification of one described by Kawabata, proceeds in four steps and requires no
1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors
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Page/Page column 26-27, (2008/06/13)
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of For
