63400-91-9

Basic information

• Product Name: 2-[(2,4-dinitrophenyl)amino]-3-(1H-indol-3-yl)propanoic acid
• CAS NO: 63400-91-9
• Molecular Formula: C₁₇H₁₄N₄O₆
• Molecular Weight: 370.321
• Mol File: 63400-91-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 699.6°Cat760mmHg
• Flash Point: 376.9°C
• Density: 1.584g/cm³
• CAS DataBase Reference: 2-[(2,4-dinitrophenyl)amino]-3-(1H-indol-3-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2,4-dinitrophenyl)amino]-3-(1H-indol-3-yl)propanoic acid(63400-91-9)
• EPA Substance Registry System: 2-[(2,4-dinitrophenyl)amino]-3-(1H-indol-3-yl)propanoic acid(63400-91-9)

Safety Data

• Hazardous Substances Data: 63400-91-9(Hazardous Substances Data)

Usage

Derived from

Tryptophan

Contains

Dinitrophenyl group

Used as

Reagent for detection and quantification of primary and secondary amines

Used in

Study of enzyme kinetics and protein structure

Potential pharmacological properties

Regulation of serotonin levels in the brain, treatment of mood and anxiety disorders

Upstream product

• 63628-23-9 N-(2,4-dinitrophenyl)-D,L-tryptophan 

Relevant articles and documents

Direct resolution of optically active isomers on chiral packings containing ergoline skeletons. 5. Enantioseparation of amino acid derivatives

A new procedure for ergot alkaloid-based chiral stationary phase preparation is described. Synthesis is based on bonding the allyl derivative of terguride to mercaptopropylsilanized silica gel. The packing exhibits higher content of chiral selector, stability, reproducibility, and enantioselectivity toward amino acids compared to that previously studied. The chromatographic behavior of amino acids with different side chains and substituent groups is investigated in order to obtain a deeper insight into the enantiodiscriminative mechanism as well as to determine the limitations and strengths of terguride as a chiral selector for this class of compounds. A variety of factors, including mobile phase parameters such as pH, ionic strength, content and nature of organic modifier, and temperature, are examined. A new procedure for ergot alkaloid-based chiral stationary phase preparation is described. Synthesis is based on bonding the allyl derivative of terguride to mercaptopropylsilanized silica gel. The packing exhibits higher content of chiral selector, stability, reproducibility, and enantioselectivity toward amino acids compared to that previously studied. The chromatographic behavior of amino acids with different side chains and substituent groups is investigated in order to obtain a deeper insight into the enantiodiscriminative mechanism as well as to determine the limitations and strengths of terguride as a chiral selector for this class of compounds. A variety of factors, including mobile phase parameters such as pH, ionic strength, content and nature of organic modifier, and temperature, are examined.