634164-38-8Relevant articles and documents
Diastereoselective intramolecular SmI2-H2O-amine mediated couplings
Dahlen, Anders,Petersson, Annika,Hilmersson, Goeran
, p. 2423 - 2426 (2003)
The effectiveness of SmI2-H2O-amine mixture for intramolecular couplings was discussed. Diastereoselectivities in the coupling of O-cyclohexanyliodophenol derivatives were provided into heterocycles. The amount of coupled product improved significantly as SmI2, the substrate and amine were premixed followed by a gradual addition of water.