634178-90-8

Upstream product

• 626-01-7 3-Iodoaniline 
• 634178-89-5 ethyl [(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-{[(tert-butyl)(dimethyl)silyl]oxy}tetrahydrofuran-2-yl]acetate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 197784-38-6 ethyl [2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]acetate 

Downstream Products

• 634178-92-0 {5-[3-(2-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-acetylamino)-phenyl]-thiazol-2-yl}-methyl-carbamic acid tert-butyl ester 
• 634178-91-9 [5-(3-{2-[5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-yl]-acetylamino}-phenyl)-thiazol-2-yl]-methyl-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Design of artificial nucleobases for the recognition of the AT inversion by triple-helix forming oligonucleotides: A structure-stability relationship study and neighbour bases effect

We report herein on the synthesis, the incorporation into triplex forming oligonucleotides (TFO) and the recognition properties of a series of synthetic nucleosides designed for the specific recognition of an inverted A·T base pair in a pyrimidine triple