634193-60-5

Upstream product

• 685895-93-6 (2R)-1-(4-methoxybenzyl)-5-oxopyrrolidine-2-carboxaldehyde 
• 82302-97-4 dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate 

Downstream Products

• 634193-61-6 (5R)-5-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-enyl]-1-(4-methoxybenzyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

EP4 RECEPTOR AGONISTS

This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the

1,5-DISTRIBUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE DISEASES SUCH AS GLAUCOMA

This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors of formula (I), their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of the patient.