6342-19-4

Basic information

• Product Name: MORPHOLIN-4-YL-PHENYL-ACETIC ACID
• Synonyms: MORPHOLIN-4-YL-PHENYL-ACETIC ACID;RARECHEM AL BO 2361;TIMTEC-BB SBB007017;ART-CHEM-BB B006309;AKOS B006309;NSC49409;2-Morpholin-4-ylphenethylamine;2-morpholino-2-phenylacetic acid
• CAS NO: 6342-19-4
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.25
• Mol File: 6342-19-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 202 °C (decomp)(Solv: benzene (71-43-2))
• Boiling Point: 347.9 °C at 760 mmHg
• Flash Point: 164.2 °C
• Appearance: /
• Density: 1.237 g/cm³
• Vapor Pressure: 1.96E-05mmHg at 25°C
• Refractive Index: 1.574
• Storage Temp.: 2-8°C
• PKA: 1.76±0.10(Predicted)
• CAS DataBase Reference: MORPHOLIN-4-YL-PHENYL-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: MORPHOLIN-4-YL-PHENYL-ACETIC ACID(6342-19-4)
• EPA Substance Registry System: MORPHOLIN-4-YL-PHENYL-ACETIC ACID(6342-19-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 6342-19-4(Hazardous Substances Data)

Usage

General Description

Morpholin-4-yl-phenyl-acetic acid is a chemical compound that consists of a morpholine ring, a phenyl group, and an acetic acid moiety. It is commonly used in research and development as a building block for the synthesis of various pharmaceuticals and drugs. MORPHOLIN-4-YL-PHENYL-ACETIC ACID has potential therapeutic implications due to its ability to modulate specific biological pathways, making it suitable for drug design and discovery. It is also used as a key intermediate in the production of advanced materials, agrochemicals, and other specialty chemicals. Its versatile chemical structure and properties make it a valuable component in the synthesis of various pharmaceutical and industrial products.

InChI:InChI=1/C12H15NO3/c14-12(15)11(10-4-2-1-3-5-10)13-6-8-16-9-7-13/h1-5,11H,6-9H2,(H,14,15)

Upstream product

• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 100609-91-4 α-morpholine methyl phenylacetate 

Downstream Products

• 31490-21-8 2-(morpholin-4-yl-phenyl-methyl)-1H-benzoimidazole 
• 897446-40-1 N-(2-aminophenyl)-2-morpholin-4-yl-2-phenylacetamide 

Relevant articles and documents

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

Design, synthesis and structure-activity relationships of benzimidazole derivatives as activators of the AMP-activated protein kinase (AMPK) are presented in this paper. AMPK is the central component of a protein kinase cascade that plays a key role in the regulation of energy balance. Once activated, AMPK initiates a series of responses that are aimed at restoring the energy balance of the cell and recent studies have indicated that AMPK plays an important role in regulation of the whole-body energy metabolism. The following study based on the lead compound S27847 involved modification of three regions of this compound. Preliminary structure-activity relationships are being described.