6342-49-0Relevant academic research and scientific papers
4-Hydroxy-3-methoxy-benzaldehyde series aroyl hydrazones: Synthesis, thermostability and antimicrobial activities
Wang, Liang,Guo, Da-Gang,Wang, Yan-Yan,Zheng, Chang-Zheng
, p. 58895 - 58901 (2015/02/19)
Efficient synthetic procedures for the preparation of aroyl hydrazones were developed by converting the corresponding ethyl ester into hydrazides, followed by a reaction with 4-hydroxy-3-methoxy-benzaldehyde. A series of aromatic hydrazides and aroyl hydrazones were characterized by elemental analysis, IR, 1H NMR, 13C NMR and thermogravimetric analysis. The thermal gravity analysis showed that the compounds 3a-3d were stable below 228.23, 227.65, 118.97 and 179.51 °C, respectively. The aromatic hydrazides and aroyl hydrazones showed antimicrobial activity towards Staplylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. The antibacterial activity experiments indicated that aroyl hydrazones had higher activity than the hydrazides. The presence of a hydroxyl group, as well as the number and position of the hydroxyl groups, were important and further enhance the antimicrobial activity. This journal is
Synthesis and biological activity of 2-hydroxy-N(5-methylene-4-oxo-2-aryl- thiazolidin-3-yl)-benzamide
Patel, Hasmukh S.,Patel, Sumeet J.
experimental part, p. 1632 - 1639 (2010/09/17)
2-Hydroxy benzoic acid hydrazide (1) undergoes facile condensation with aromatic aldehydes to afford the corresponding 2-hydroxy benzoic acid arylidene hydrazides (2a-h) in good yields. Cyclocondensation of compounds 2a-h with thioglycolic acid yields 2-hydroxy-N(4-oxo-2-aryl-thiazolidin-3-yl)-benzamides (3a-h). These 3a-h compounds are for the reacted with benzaldehyde in the presence of sodium ethanolate affords, giving 2-hydroxy-N(5-methylene-4-oxo-2- aryl-thiazolidin-3-yl)-benzamides (4a-h). The structures of these compounds were established on the basis of analytical and spectral data. All the newly synthesized compounds were evaluated for their antibacterial and antifungal activities. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
PHYSICO-CHEMICALS INVESTIGATION ON SOME ACID HYDRAZIDE SCHIFF BASE CHELATES OF Ni(II) AND Cu(II)
Agarwal, Suresh K.,Gupta, Rajiva,Kumar, Dinesh
, p. 329 - 335 (2007/10/02)
The chelation tendency of vanillidene salicylic acid hydrazide, anisylidene anthranilic acid hydrazide and veratrylidene benzoic acid hydrazide towards Ni(II) and Co(II) has been investigated.The isolated metal chelates have been characterized on the basi
Uranyl Nitrate Complexes of Some Schiff Bases Derived from Substituted Benzaldehydes and Amino Compounds
Devi, G. Sobhana,Indrasenan, P.
, p. 809 - 811 (2007/10/02)
Complexes of uranyl nitrate with ten schiff bases have been prepared and characterised on the basis of analytical, conductance, molecular weight and spectral data.The schiff bases used are; N-(3-methoxy-4-hydroxybenzylidene)benzhydrazone (MHBBH), N-(3-met
