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Usage

Uses

Used in Pharmaceutical Industry:
[1-(ethoxycarbonyl)-2-oxocyclopentyl]acetic acid is used as a building block in organic synthesis for the development of various pharmaceuticals. Its unique structure suggests that it may contribute to the creation of novel drugs with potential applications in treating different medical conditions.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, [1-(ethoxycarbonyl)-2-oxocyclopentyl]acetic acid is utilized as a key component in the synthesis of various agrochemicals. Its incorporation into these products may enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Potential for Biological Activity:
Given the structure of [1-(ethoxycarbonyl)-2-oxocyclopentyl]acetic acid, it may possess biological activity that could be of interest for the development of new drugs. However, further research and testing are necessary to determine its specific properties and potential applications in this area.

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 

Downstream Products

• 33668-25-6 ethyl 3-oxocyclohexanecarboxylate 
• 25017-79-2 ethyl 3-oxocyclohex-1-ene-1-carboxylate 

Relevant academic research and scientific papers

Rearrangements of α-Diazo-β-hydroxyketones for the Synthesis of Bicyclo[m.n.1]alkanones

Rhodium-catalyzed decomposition of fused bicyclic α-diazo-β-hydroxyketones results in good yields of bridged bicyclo[m.n.1]ketones via a rearrangement pathway.

Free-Radical Ring Expansion by one Carbon Atom by Decomposition of the Thiohydroxamic Esters of (1-Alkoxycarbonyl-2-oxocycloalkyl)acetic Acids

A free-radical ring expansion by one carbon atom has been achieved by thermal decomposition of thiohydroxamic esters of (1-alkoxycarbonyl-2-oxocycloalkyl)acetic acids, 8.Thus, by decomposition of thiohydroxamic esters 8a-f in boiling toluene, ethyl 3-oxocycloalkenecarboxylates 9a-f are obtained as principal ring-enlarged products in 27-58percent yield; accompanied by ethyl 1-(4-methyl-2-thiazolylthio)-3-oxocycloalkane-1-carboxylates 10c,d (24percent yield) with the ring expanded by one carbon atom.Unrearranged ethyl 1-(4-methyl-2-thiazolylthiomethyl)-2-oxocycloalkane-1-carboxylates) 11a-f are formed as side products (8-17percent yield).Ring expansion involves the following sequence of reactions: 3-exo-cyclization (to C=O grup), cleavage of the cyclopropane ring, intermolecular addition to the thione group of thiohydroxamic esters and elimination reaction.