63425-54-7

Basic information

• Product Name: 3-CHLORO-1-METHYL-1H-PYRAZOLE
• Synonyms: 3-CHLORO-1-METHYL-1H-PYRAZOLE;3-CHLORO-1-METHYL-1H-PYRAZOLE(L);3-Chloro-1-methylpyrazole;1-Methyl-3-chloropyrazole
• CAS NO: 63425-54-7
• Molecular Formula: C₄H₅ClN₂
• Molecular Weight: 116.55
• Mol File: 63425-54-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 159℃
• Flash Point: 50℃
• Appearance: /
• Density: 1.26
• Storage Temp.: 2-8°C
• PKA: -0.27±0.10(Predicted)
• CAS DataBase Reference: 3-CHLORO-1-METHYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-1-METHYL-1H-PYRAZOLE(63425-54-7)
• EPA Substance Registry System: 3-CHLORO-1-METHYL-1H-PYRAZOLE(63425-54-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 23-26-36/37/39
• Hazardous Substances Data: 63425-54-7(Hazardous Substances Data)

Usage

General Description

3-Chloro-1-methyl-1H-pyrazole is a chemical compound with the molecular formula C4H6ClN2. It is a pyrazole derivative with a chlorine atom and a methyl group attached to the pyrazole ring. 3-CHLORO-1-METHYL-1H-PYRAZOLE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It can also be used as a research reagent in chemical and biochemical studies. 3-Chloro-1-methyl-1H-pyrazole has potential applications in various fields due to its versatile properties and reactivity. However, it is important to handle this chemical with care and follow proper safety procedures due to its potential hazards.

Upstream product

• 1904-31-0 methyl-1 amino-3 pyrazole 

Downstream Products

• 299930-70-4 3-chloro-1-methyl-4-nitro-1H-pyrazole 
• 50877-48-0 Toluene-4-sulfonate5-chloro-1,2-dimethyl-2H-pyrazol-1-ium; 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.

SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to pyrimidine compounds of formula (I), their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to process of preparation of these pyrimidine compounds, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases and disorders mediated by epidermal growth factor receptor (EGFR) family kinases.