63429-99-2

Basic information

• Product Name: 5-CHLORO-2-METHOXYPHENYL ISOTHIOCYANATE
• Synonyms: 5-CHLORO-2-METHOXYPHENYL ISOTHIOCYANATE;4-CHLORO-2-ISOTHIOCYANATO-1-METHOXY-BENZENE;2-Methoxy-5-chlorophenyl isothiocyanate;benzene, 4-chloro-2-isothiocyanato-1-methoxy-;4-Chloro-2-isothiocyanatoanisole, 4-Chloro-2-isothiocyanato-1-methoxybenzene;5-Chloro-2-methoxyphenyl isothiocyate, 98%
• CAS NO: 63429-99-2
• Molecular Formula: C₈H₆ClNOS
• Molecular Weight: 199.66
• Mol File: 63429-99-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 56-59°C
• Boiling Point: 164-165°C
• Flash Point: 164-165°C
• Appearance: /
• Density: 1.23 g/cm³
• Vapor Pressure: 0.000488mmHg at 25°C
• Refractive Index: 1.572
• Sensitive: Moisture Sensitive
• BRN: 2719683
• CAS DataBase Reference: 5-CHLORO-2-METHOXYPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-2-METHOXYPHENYL ISOTHIOCYANATE(63429-99-2)
• EPA Substance Registry System: 5-CHLORO-2-METHOXYPHENYL ISOTHIOCYANATE(63429-99-2)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: 20/21/22-36/37/38-43
• Safety Statements: 26-36/37/39-36/37
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 63429-99-2(Hazardous Substances Data)

Usage

General Description

5-Chloro-2-methoxyphenyl isothiocyanate is a chemical compound that belongs to the class of isothiocyanates, which are organic compounds containing the functional group -NCS. It is a derivative of phenyl isothiocyanate, with a chlorine atom and a methoxy group attached to the phenyl ring. 5-CHLORO-2-METHOXYPHENYL ISOTHIOCYANATE is commonly used in organic synthesis as a reagent for the introduction of the isothiocyanate functional group onto other molecules, allowing for the production of various sulfur-containing organic compounds. It is also used as a building block for the synthesis of pharmaceuticals and agrochemicals. Additionally, its properties as a potent pesticide and fungicide make it a valuable chemical for industrial and agricultural applications. However, it is important to handle this compound with care, as it can be hazardous if not used properly.

InChI:InChI=1/C8H6ClNOS/c1-11-8-3-2-6(9)4-7(8)10-5-12/h2-4H,1H3

Upstream product

• 463-71-8 thiophosgene 
• 95-03-4 5-chloro-2-methoxyaniline 

Downstream Products

• 1039924-36-1 4-(5-chloro-2-methoxyphenyl)-3-thiosemicarbazide 
• 137-52-0 N-[2-methoxy-5-chlorophenyl]-3-hydroxy-2-naphthalene carboxamide 
• 63980-69-8 (2-methoxy-5-chlorophenyl)-2-thiourea 
• 1152595-02-2 O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 5-chloro-2-methoxyphenylthiocarbamate 
• 1065641-49-7 methyl N-5-chloro-2-methoxyphenyl-N'-cyanocarbamimidothioate 
• 187866-52-0 2-[3-(5-chloro-2-methoxyphenyl)-thioureido]-acetamide 

Relevant articles and documents

USP8 inhibitor, preparation method and applications thereof

The invention discloses a USP8 inhibitor, a preparation method and applications thereof, belongs to the field of medicinal chemistry, and particularly relates to a class of USP8 inhibitors (I) containing substituted thiourea or substituted guanidine derivatives, and a preparation method thereof. According to the invention, the results of biological experiments prove that the compound has good USP8inhibitory activity and cell activity and can be used for treating diseases such as malignant tumors and the like.