63430-52-4Relevant academic research and scientific papers
Cu-Catalyzed Intermolecular-Site C-H Amination of Cyclohexenone Derivatives: The Benefit of Bifunctional Ligands
Chen, Zi-Sheng,Ji, Kegong,Yang, Fang,Zhao, Xin,Zhou, Qian-Qian,Zou, Shao-Yu
, p. 1732 - 1741 (2022/01/28)
Utilizing 1,10-phenanthroline-Type bifunctional ligands, an efficient Cu-catalyzed intermolecular site-selective remote C-H amination using cyclohexenone derivatives and anilines was realized. The amide group installed on the bifunctional ligand played a
HISTONE DEMETHYLASE INHIBITORS
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Paragraph 00171; 00204, (2016/04/09)
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
