6344-41-8Relevant academic research and scientific papers
SUBSTITUTED CYCLOALKYLS AS MODULATORS OF THE INTEGRATED STRESS PATHWAY
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Page/Page column 372, (2020/11/12)
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions.
Sydnone Cycloaddition Route to Pyrazole-Based Analogs of Combretastatin A4
Brown, Andrew W.,Fisher, Matthew,Tozer, Gillian M.,Kanthou, Chryso,Harrity, Joseph P. A.
, p. 9473 - 9488 (2016/11/11)
The combretastatins are an important class of tubulin-binding agents. Of this family, a number of compounds are potent tumor vascular disrupting agents (VDAs) and have shown promise in the clinic for cancer therapy. We have developed a modular synthetic r
Synthesis of 2 H-indazoles by the [3 + 2] dipolar cycloaddition of sydnones with arynes
Fang, Yuesi,Wu, Chunrui,Larock, Richard C.,Shi, Feng
experimental part, p. 8840 - 8851 (2012/01/02)
A rapid and efficient synthesis of 2H-indazoles has been developed using a [3 + 2] dipolar cycloaddition of sydnones and arynes. A series of 2H-indazoles have been prepared in good to excellent yields using this protocol, and subsequent Pd-catalyzed coupl
Synthesis and reactions of 9,10-diazatetracyclo-[6.3.0.0.4,110.5.9]undecanes
Gribble, Gordon W.,Hirth, Bradford H.
, p. 719 - 726 (2007/10/03)
The tandem 1,3-dipolar cycloaddition between sydnones and 1,5-cyclooctadiene provides 9,10-diazatetracyclo[6.3.0.0.4,110.5,9]undecanes (the Weintraub reaction) in modest to good yields.
Reaction of Sydnones with Oxygen
Nakajima, Masayuki,Anselme, Jean-Pierre
, p. 1444 - 1448 (2007/10/02)
The reaction of 3-benzyl- and 3-(p-chlorobenzyl)-4-phenylsydnones (1a and 1b) and of 3-benzylsydnone (1c) with oxygen at room temperature in the dark is described.Possible rationalizations for the formation of the products obtained are suggested.
