634469-90-2

Basic information

• Product Name: 4-Piperidinecarbonitrile, 4-(3-chlorophenyl)-1-[(4-pyrazinyl-1-piperazinyl)acetyl]-
• CAS NO: 634469-90-2
• Molecular Formula: C22H25ClN6O
• Molecular Weight: 424.933
• Mol File: 634469-90-2.mol

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarbonitrile, 4-(3-chlorophenyl)-1-[(4-pyrazinyl-1-piperazinyl)acetyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarbonitrile, 4-(3-chlorophenyl)-1-[(4-pyrazinyl-1-piperazinyl)acetyl]-(634469-90-2)
• EPA Substance Registry System: 4-Piperidinecarbonitrile, 4-(3-chlorophenyl)-1-[(4-pyrazinyl-1-piperazinyl)acetyl]-(634469-90-2)

Safety Data

• Hazardous Substances Data: 634469-90-2(Hazardous Substances Data)

Upstream product

• 634468-46-5 1-(2-chloroacetyl)-4-(3-chlorophenyl)-4-piperidinecarbonitrile 
• 34803-68-4 1-(pyrazin-2-yl)piperazine 

Relevant articles and documents

Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof

The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; p is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents an aromatic group selected from: the said aromatic groups being unsubstituted or being mono- or disubstituted by a substituent selected independently from a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; Preparation process and therapeutic application.